After the capture of Cyprus, the Europeans began to organise a new crusade navy. The navy was commanded by Don Juan and it was emerged by the ships of Venice, Spain, Malta, Vatican and the other Italian governments. Experienced admirals of the Ottoman Navy, Pertev Pasha and Uluc Ali Pasha recommended a defence war, but Ali Pasha the Minister of Navy made the first attack.

The war taken place in the North of the island of Morea on 7th October 1571. In the end of the war the Ottomans were defeated and Ali Pasha had died. Uluc Ali Pasha was rescued his ships and he replaced Ali Pasha.

This defeat declined the Ottoman authority in the seas and in the trading roads.